I'm running windows 7 home premium, on the same settings I ran NWN under vista, and have no problems.
If your system will run it under vista, it should run it under 7. The issue though, is not every setup will run NWN under vista. In my case, I have to turn off V-Sync or I crash immediately when booting into NWN. Other than that, Win XP emulation mode, and run it in administrator mode.