This appears to be a minor issue, only apparently affecting animals that flee or fly away, but I haven't explored it enough to make sure there's no suddenly-dangerous NPCs that aren't affected.
Where: Village of Barovia - Mad Mary's House
When: After following through the dialogue, and prompting Mad Mary to attack the player character.
What: Many of the neutral animals around Barovia, including ravens, and vista chiri, appear to be instantly hostile to my character. I'm guessing that the dialogue with Mad Mary changes a faction reaction, and she's in the same faction as these animals? I don't really know how reactions work in NWN. This persists until a server reset, I've had it happen multiple times- I can confidently say every single time I've gone through the dialogue with Mary.
It really is little issue for ravens and birds, but if a non-wildlife NPC is causing it, I can see it being in the realm of reason that it might affect other, actually problematic NPCs. It would be awful to find out that Horatiu in the ML temple suddenly hates me, because of my conversation with Mary, to give an entirely false example.